ERC-20 on Base · OralInsulin

No needle. No blood. Just protection, release and delivery.

ORIN is the project token for the Oral Insulin Network: a neutral network for researchers, developers, manufacturers, clinicians, payers, channels and capital to act on the evidence an oral insulin needs.

Get ORIN →Read the whitepaper

by OralInsulin · launched on wrapped.news · paired with wNEWS

Protection · hexamer closed

The hexamer

Insulin is naturally stored as a zinc-stabilized hexamer: six insulin molecules assembled around zinc. To become biologically active, that structure separates into individual molecules. The ORIN mark captures that transition.

Protection

Its hexagonal carrier protects the insulin.

Release

Then opens to create a route from inside to outside.

Delivery

No needle and no blood, just protection, release and delivery.

Public proof

The public account of oral insulin has run ahead of its evidence.

Published reviews list between eight and twelve oral programs that reached clinical trials, and no approval by a major regulator.

8–12

oral programs reached clinical trials

approvals by a major regulator

58 / 89

registry studies retrieved vs reported, Sep 18 2026

710

patients in a phase 3 that missed both endpoints

Basis → whitepaper references

What circulates

What the record supports

Basis

Buccal insulin is approved in four countries

Company statements only; no regulator’s register entry was located

[5, 25]

Oral insulin lowered HbA1c in trials

In phase 2. The 710-patient phase 3 trial missed both endpoints

[5, 22]

Oral insulin does not work

An oral basal insulin matched injected glargine on fasting glucose over eight weeks, then was stopped on dose and cost

[21]

Oral peptides are a solved problem

Oral semaglutide is approved; in 2025 it was under a tenth of its molecule’s sales (arithmetic on company figures)

[7, 28]

Patients prefer a pill

76.5 percent in the abstract; 52.5 percent after seeing the administration steps

[32]

A pill will be taken more reliably

No study was located linking a change of insulin route to adherence or cost

[7]

How the network works

Rewarding useful work and audited accuracy, never approvals or volume.

Inferred · not adopted

Evidence bond

A proposing agent posts a bond in ORIN with each record it submits to the review queue. The bond is returned when the record is published and survives its audit window. A fraction is forfeited only for an avoidable error; reporting that a figure is not published never forfeits it.

Derived from NEWS stake-and-slash, applied to records, not opinions

Participation condition

E[π] = q·r − (1 − q)·σ·b

Positive only when audited accuracy q exceeds σb / (r + σb). The owner chooses one number, the accuracy q₀ below which participation should lose money. No value of q₀, b, σ or r is proposed.

⬡A proposer never verifies its own work.

⬡The source decides, not a vote.

⬡Reporting that a figure is not published is a completed record.

Try the bond condition in Learn →

The token

Fixed supply. Minted once.

ORIN

OralInsulin · ERC-20 on Base

Project participation, proposed staking and compensation.

wNEWS

Wrapped News Token · Base

Initial ORIN trading pair and launch funding route.

No owner

Supply minted in the constructor

No mint

Rewards come only from launch allocation

No pause

Transfers cannot be halted

No fee

No transfer tax

No upgrade

No proxy, no upgrade path

The initial launch model deposits ORIN alone. Buyers supply wNEWS as they purchase ORIN. The resulting wNEWS principal remains in the liquidity position in that model.

Once the band is exhausted its wNEWS supports return sales across the original range, finite and only while the position remains deposited. It does not set a floor. Liquidity above the band is expected from holders, not committed by anyone. Section 5 of the whitepaper →

PairORIN / wNEWS

Launch priceopen

Allocationopen

Contract0x…TBD

Ask the evidence

Ask a question. Get the record, not a guess.

Every number comes from a sourced record, every answer shows the tool calls behind it, and where the record publishes nothing, it says so.

For agents · x402

# Unpaid call returns the price list
$ curl -i -X POST https://oralinsulin.org/ask
HTTP/2 402
{
  "accepts": [
    { "asset": "USDC",  "network": "base" },
    { "asset": "wNEWS", "note": "0.8x" },
    { "asset": "ORIN",  "note": "at launch" }
  ],
  "free_alternative": "POST /mcp"
}

Every record the endpoint reads stays free at POST /mcp (agent card at /.well-known/agent.json). The wallet signs; nothing is held here.